KMID : 0614620220790030099
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Korean Journal of Gastroenterology 2022 Volume.79 No. 3 p.99 ~ p.108
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Diagnosis and Treatment of Eosinophilic Esophagitis
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Kim Su-Jin
Choi Cheol-Woong Hwang Cheong-Su
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Abstract
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Eosinophilic esophagitis (EoE) is a chronic, immune/antigen-mediated esophageal disease characterized by symptoms of esophageal dysfunction and eosinophil-predominant inflammation. The diagnostic criteria for EoE have changed with our growing knowledge over the past two decades. Esophageal eosinophilia, which responds histologically to a proton pump inhibitor (PPI) is not a distinct disease but a subset of EoE. An endoscopic scoring system that relies on the assessment of exudates, rings, edema, furrows, and strictures is a useful tool for assessing endoscopic severity. PPIs are regarded as safe and effective first-line treatments for EoE.
Oral topical corticosteroids or dietary therapy are also options for first-line treatment. Endoscopic dilation is effective for relieving the dysphagia symptoms of a patient with an esophageal stricture.
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KEYWORD
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Eosinophilic esophagitis, Proton pump inhibitors, Steroids
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